@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RAxfNMrBvfY_RQfP2jDUuVScoj6WeYT3Z4QPd7hNJHelM> .
@prefix sub: <http://purl.org/np/RAxfNMrBvfY_RQfP2jDUuVScoj6WeYT3Z4QPd7hNJHelM#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo .
}

sub:assertion {
  sub:association a rdf:Statement;
    rdf:object <https://identifiers.org/MONDO:0021668>;
    rdf:predicate biolink:treats;
    rdf:subject <https://identifiers.org/CHEBI:3758>;
    rdfs:label "Clonidine hydrochloride injection is indicated in combination with opiates for the treatment of severe pain in cancer patients that is not adequately relieved by opioid analgesics alone";
    biolink:association_type biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation;
    biolink:provided_by "NeuroDKG";
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d2b11e61-b2ef-4d20-8973-a4afc6b951ae>;
    biolink:relation schema:TreatmentIndication .
  
  sub:cohort biolink:has_phenotype <https://identifiers.org/MONDO:0005070> .
  
  <https://identifiers.org/CHEBI:3758> biolink:category biolink:Drug .
  
  <https://identifiers.org/MONDO:0021668> biolink:category biolink:Disease .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB";
    npx:hasSignature "doi/Ouiu7ge+uIGa/E6niSLMa6GJo4JCU3ajg0qo5Kz0k2gP+Q1lxanZYcfg0fD5invX4lEkXE+h/fJEtDhZSO9G8hEvDK/nmtj8DSdGybEtamne3s7VKziRF/1XPZXH1QA1vT4VEv/t67j/ODSS/kx3TkQqQhiHJOGo9/I6ZGM=";
    npx:hasSignatureTarget this: .
  
  this: dcterms:created "2021-03-28T18:46:36.208+02:00"^^xsd:dateTime;
    dcterms:creator orcid:0000-0002-1468-3557;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RA59AEpaWRaR9sjdA0-n4zaQWdiZ6--iGafMrjrDAOheI> .
}