Nanopublication

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https://w3id.org/kpxl/ios/ds/np/RApCUXhnavgYV8sYh3HPmf4zo_R6y4HfcYvl7joLMyjHA

Formats

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Content

@prefix this: <https://w3id.org/kpxl/ios/ds/np/RApCUXhnavgYV8sYh3HPmf4zo_R6y4HfcYvl7joLMyjHA> .
@prefix sub: <https://w3id.org/kpxl/ios/ds/np/RApCUXhnavgYV8sYh3HPmf4zo_R6y4HfcYvl7joLMyjHA#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix ns1: <http://purl.org/np/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo .
}

sub:assertion {
  sub:spi a <https://w3id.org/linkflows/superpattern/terms/SuperPatternInstance>;
    rdfs:label "A regulatory element within the first intron of FTO affects IRX3 and IRX5 expression during early adipogenesis";
    <https://w3id.org/linkflows/superpattern/terms/hasContextClass> <http://purl.org/np/RAtsHwzNs36rGrLnoSbGrPD351Qw033Acoe4zmdXhsYlM#early-human-adipogenesis>;
    <https://w3id.org/linkflows/superpattern/terms/hasObjectClass> <http://purl.org/np/RAwkXiTv7qCtqOYzlR6ozZRGLRtG6mlogrYdRQ1E4dRDg#expression-of-genes-IRX3-and-IRX5>;
    <https://w3id.org/linkflows/superpattern/terms/hasQualifier> <https://w3id.org/linkflows/superpattern/terms/generallyQualifier>;
    <https://w3id.org/linkflows/superpattern/terms/hasRelation> <https://w3id.org/linkflows/superpattern/terms/affects>;
    <https://w3id.org/linkflows/superpattern/terms/hasSubjectClass> <http://purl.org/np/RAxLYvJ1JrRf2JAowYGbGJleQPmqtpXnXsIvse7GmLeT8#regulatory-element-within-the-first-intron-of-FTO> .
}

sub:provenance {
  sub:activity a <https://w3id.org/linkflows/superpattern/terms/FormalizationActivity>;
    prov:used <https://doi.org/10.1056/NEJMoa1502214>, sub:quote;
    prov:wasAssociatedWith orcid:0000-0003-2432-4125 .
  
  sub:assertion prov:wasGeneratedBy sub:activity .
  
  sub:quote prov:value "The rs1421085 T-to-C single-nucleotide variant disrupts a conserved motif for the ARID5B repressor, which leads to derepression of a potent preadipocyte enhancer and a doubling of IRX3 and IRX5 expression during early adipocyte differentiation.";
    prov:wasQuotedFrom <https://doi.org/10.1056/NEJMoa1502214> .
}

sub:pubinfo {
  orcid:0000-0002-1267-0234 foaf:name "Tobias Kuhn" .
  
  orcid:0000-0003-2432-4125 foaf:name "Amelia Joslin" .
  
  sub:author-list rdf:_1 orcid:0000-0003-2432-4125 .
  
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQD4Wj537OijfOWVtsHMznuXKISqBhtGDQZfdO6pbb4hg9EHMcUFGTLbWaPrP783PHv8HMAAPjvEkHLaOHMIknqhaIa5236lfBO3r+ljVdYBElBcLvROmwG+ZGtmPNZf7lMhI15xf5TfoaSa84AFRd5J2EXekK6PhaFQhRm1IpSYtwIDAQAB";
    npx:hasSignature "ir8i/lid0qJdL3r1A0r88pq0/XDOVb9XdRxAvsb95TYju6NXBF6OBfLcsz/nEgJ3nGQagKQAFT24d3flmc1zAb+BDO3Ewoq1j/ngmn7nPsYb57D0OFFAKpSGdDJdD8DEWOiejuKGbN+VuW5c3zwRU5MS3VJQpEGRFZym2YuMFbs=";
    npx:hasSignatureTarget this:;
    npx:signedBy orcid:0000-0002-1267-0234 .
  
  this: dct:created "2024-07-12T07:23:33.284Z"^^xsd:dateTime;
    dct:creator orcid:0000-0002-1267-0234;
    dct:isPartOf <https://doi.org/10.3233/DS-210038>;
    dct:license <https://creativecommons.org/licenses/by/4.0/>;
    npx:hasNanopubType <https://w3id.org/kpxl/ios/ds/terms/DataScienceNanopub>;
    npx:introduces sub:spi;
    npx:wasCreatedAt <https://nanodash.knowledgepixels.com/>;
    <http://purl.org/ontology/bibo/authorList> sub:author-list;
    prov:wasDerivedFrom ns1:RAxBBJ2WkonyQNlXfdCAOaCi64J_xqgVGeaLjVQow9M88;
    <https://w3id.org/linkflows/reviews/isUpdateOf> ns1:RAxxJWyH8OdTJLs-ZY1q5jVq1OWFNOoLFvwEcUFyR8EEo;
    nt:wasCreatedFromProvenanceTemplate ns1:RAB_oy10D3XUP-zYlqGz7Uj58AsUXhEKeGqmRFg5LSgDM;
    nt:wasCreatedFromPubinfoTemplate ns1:RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM,
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      <https://w3id.org/np/RAIabr2sRVJ-YOIwZRD__BVMJKnq3QtQw_mjLIGSACPAI>, <https://w3id.org/np/RA_JdI7pfDcyvEXLr_gper3h8egmNggeTqkJbyHrlMEdo>,
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}