[ { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64#Head", "@graph": [ { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64", "http://www.nanopub.org/nschema#hasAssertion": [ { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64#assertion" } ], "http://www.nanopub.org/nschema#hasProvenance": [ { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64#provenance" } ], "http://www.nanopub.org/nschema#hasPublicationInfo": [ { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64#pubInfo" } ], "@type": [ "http://www.nanopub.org/nschema#Nanopublication" ] } ] }, { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64#pubInfo", "@graph": [ { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64#sig", "http://purl.org/nanopub/x/hasAlgorithm": [ { "@value": "RSA" } ], "http://purl.org/nanopub/x/hasPublicKey": [ { "@value": "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB" } ], "http://purl.org/nanopub/x/hasSignature": [ { "@value": "gLgQ9Pk7ScyXOAFVn50Ok7arnpWYr9ob/vLZr5j3dBbRxjlHVaY7BwaMUcqOkdWdTbRpu80pblV/bm4dCeRWR/Ck4wKirMD2RpFShlMg/34oCdOjboituNg7My0GfjZQ8qab/FA2fxnRLE3/R2Zzk/ARpaPFMsEsDEHCyWoqH7w=" } ], "http://purl.org/nanopub/x/hasSignatureTarget": [ { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64" } ] }, { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64", "http://www.w3.org/ns/prov#generatedAtTime": [ { "@value": "2022-09-16T11:53:03.563580", "@type": "http://www.w3.org/2001/XMLSchema#dateTime" } ], "http://www.w3.org/ns/prov#wasAttributedTo": [ { "@id": "https://orcid.org/0000-0002-1501-1082" } ], "https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate": [ { "@id": "http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY" } ] }, { "@id": "https://w3id.org/biolink/vocab/", "http://purl.org/pav/version": [ { "@value": "2.3.0" } ] } ] }, { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64#assertion", "@graph": [ { "@id": "http://identifiers.org/drugbank/DB01221", "@type": [ "https://w3id.org/biolink/vocab/Drug" ], "http://www.w3.org/2000/01/rdf-schema#label": [ { "@value": "Ketamine" } ], "https://w3id.org/biolink/vocab/category": [ { "@id": "https://w3id.org/biolink/vocab/Drug" } ] }, { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64#association", "http://www.w3.org/1999/02/22-rdf-syntax-ns#object": [ { "@id": "http://www.ebi.ac.uk/efo/EFO_0009854" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate": [ { "@id": "https://w3id.org/biolink/vocab/treats" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject": [ { "@id": "http://identifiers.org/drugbank/DB01221" } ], "@type": [ "https://w3id.org/biolink/vocab/ChemicalToDiseaseOrPhenotypicFeatureAssociation" ], "http://www.w3.org/2000/01/rdf-schema#label": [ { "@value": "Off-label ketamine treatment has shown acute antidepressant effects that offer hope for patients with therapy-resistant depression. However, its potential for integration into treatment algorithms is controversial, not least because the evidence base for maintenance treatment with repeated ketamine administration is currently weak. Ketamine is also a drug of misuse, which has raised concerns regarding the target population." } ], "https://w3id.org/biolink/vocab/aggregator_knowledge_source": [ { "@id": "https://w3id.org/biolink/infores/knowledge-collaboratory" } ], "https://w3id.org/biolink/vocab/category": [ { "@id": "https://w3id.org/biolink/vocab/ChemicalToDiseaseOrPhenotypicFeatureAssociation" } ], "https://w3id.org/biolink/vocab/has_population_context": [ { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64#context" } ], "https://w3id.org/biolink/vocab/publications": [ { "@id": "http://www.ncbi.nlm.nih.gov/pubmed/30202601" } ], "https://w3id.org/biolink/vocab/relation": [ { "@id": "http://purl.obolibrary.org/obo/NCIT_C94303" } ] }, { "@id": "http://www.ebi.ac.uk/efo/EFO_0009854", "@type": [ "https://w3id.org/biolink/vocab/Disease" ], "http://www.w3.org/2000/01/rdf-schema#label": [ { "@value": "Treatment resistant depression" } ], "https://w3id.org/biolink/vocab/category": [ { "@id": "https://w3id.org/biolink/vocab/Disease" } ] }, { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64#context", "@type": [ "https://w3id.org/biolink/vocab/Cohort" ], "http://www.w3.org/2000/01/rdf-schema#label": [ { "@value": "adults" } ], "https://w3id.org/biolink/vocab/category": [ { "@id": "https://w3id.org/biolink/vocab/Cohort" } ] } ] }, { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64#provenance", "@graph": [ { "@id": "http://purl.org/np/RAY4X2_asozKCdK12ii9Wx3jgih4zAvB1PvnrRAJspG64#assertion", "http://www.w3.org/ns/prov#wasAttributedTo": [ { "@id": "https://orcid.org/0000-0002-7641-6446" } ] } ] } ]