@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RANL2PUfRN6-Ps9oO3AVs2NuyWjccP8yPINMnwRbCtUzY> .
@prefix sub: <http://purl.org/np/RANL2PUfRN6-Ps9oO3AVs2NuyWjccP8yPINMnwRbCtUzY#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix orcid: <https://orcid.org/> .
@prefix nkg: <https://w3id.org/neurodkg/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo .
}

sub:assertion {
  <http://purl.bioontology.org/ontology/MEDDRA/10061334> schema:possibleTreatment sub:medtherapy .
  
  sub:medtherapy prov:wasDerivedFrom sub:quote;
    schema:drug <http://identifiers.org/drugbank/DB00555>;
    schema:targetPopulation sub:targetpop;
    nkg:indicationType schema:TreatmentIndication .
  
  sub:quote prov:value "Lamotrigine tablets are indicated for conversion to monotherapy in adults (aged 16 years and older) with partial-onset seizures who are receiving treatment with carbamazepine, phenytoin, phenobarbital, primidone, or valproate as the single antiepileptic drug (AED).";
    prov:wasQuotedFrom <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0b0f0209-edbd-46f3-9bed-762cbea0d737> .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB";
    npx:hasSignature "iYDaKVyQ3sBx9HISJb0U1dRcdORAGJ3bj/yyFnrfj6IfIpPPeBPGJsmJXY0+UMiiMxtAm7WDUT0NCoAWWyRoDW5cLZNu/pv7lM/RymMRfmDOkluMOkonMcrOGAGqtfqLruXjDoD9TNR3nxmP6t+xYe5pRj/FZ/+Pl8TsAQCSlrA=";
    npx:hasSignatureTarget this: .
  
  this: dcterms:created "2021-04-03T10:15:21.156+02:00"^^xsd:dateTime;
    dcterms:creator orcid:0000-0002-1468-3557;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RA64ptuigOfVGfIhpdwWeJnssaHV9jTQCnAm6Pvgrvmos> .
}