http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs
.trig | .trig.txt | .jelly | .jelly.txt
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs> .
@prefix sub: <http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix ncit: <http://purl.obolibrary.org/obo/NCIT_> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
sub:Head {
this: a np:Nanopublication;
np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubinfo .
}
sub:assertion {
ncit:C15675 rdfs:label "Adjuvant Therapy, any therapy that is administered to augment or stimulate other treatment modalities or to minimize or prevent disease recurrence subsequent to the main treatment plan. " .
sub:assertion a nt:AssertionTemplate;
rdfs:label "Defining a drug indication with its context (BioLink model)";
nt:hasStatement sub:st00, sub:st01, sub:st02, sub:st03, sub:st04, sub:st05, sub:st06,
sub:st07, sub:st08, sub:st09, sub:st10, sub:st11, sub:st12, sub:st13, sub:st14 .
sub:association a nt:LocalResource;
rdfs:label "this association" .
sub:associationRelation a nt:GuidedChoicePlaceholder;
rdfs:label "provide the type of drug indication";
nt:possibleValue ncit:C15675, schema:ApprovedIndication, schema:PreventionIndication,
schema:TreatmentIndication, nkg:OffLabelIndication, nkg:SymptomaticReliefIndication .
sub:cohort a nt:LocalResource;
rdfs:label "the study cohort" .
sub:cohortAgeLabel a nt:LiteralPlaceholder;
rdfs:label "describe the life stage or age of the cohort (e.g. Adults)" .
sub:cohortAgeMax a nt:LiteralPlaceholder;
rdfs:label "describe the maximum age of the cohort (e.g. 80)" .
sub:cohortAgeMin a nt:LiteralPlaceholder;
rdfs:label "describe the minimum age of the cohort (e.g. 7)" .
sub:hasPhenotype a nt:GuidedChoicePlaceholder;
rdfs:label "provide additional phenotypes for the cohort";
nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .
sub:object a nt:GuidedChoicePlaceholder;
rdfs:label "search for the disease it treats";
nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .
sub:publication a nt:UriPlaceholder;
rdfs:label "add the URL of a publication supporting this association (doi, PubMed...)" .
sub:readableassertion a nt:LiteralPlaceholder;
rdfs:label "describe the assertion concisely (e.g. tylenol treats pain in adults patients)" .
sub:st00 a rdf:Statement;
rdf:object sub:readableassertion;
rdf:predicate rdfs:label;
rdf:subject sub:association;
nt:statementOrder "0"^^xsd:integer .
sub:st01 a rdf:Statement;
rdf:object sub:subject;
rdf:predicate rdf:subject;
rdf:subject sub:association;
nt:statementOrder "1"^^xsd:integer .
sub:st02 a rdf:Statement;
rdf:object sub:object;
rdf:predicate rdf:object;
rdf:subject sub:association;
nt:statementOrder "3"^^xsd:integer .
sub:st03 a rdf:Statement;
rdf:object biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation;
rdf:predicate biolink:association_type;
rdf:subject sub:association;
nt:statementOrder "19"^^xsd:integer .
sub:st04 a rdf:Statement;
rdf:object sub:associationRelation;
rdf:predicate biolink:relation;
rdf:subject sub:association;
nt:statementOrder "6"^^xsd:integer .
sub:st05 a rdf:Statement;
rdf:object <https://w3id.org/um/NeuroDKG>;
rdf:predicate biolink:provided_by;
rdf:subject sub:association;
nt:statementOrder "22"^^xsd:integer .
sub:st06 a nt:OptionalStatement;
rdf:object sub:publication;
rdf:predicate biolink:publications;
rdf:subject sub:association;
nt:statementOrder "10"^^xsd:integer .
sub:st07 a nt:GroupedStatement, nt:OptionalStatement;
nt:hasStatement sub:st07a, sub:st07b, sub:st07c;
nt:statementOrder "11"^^xsd:integer .
sub:st07a a rdf:Statement;
rdf:object sub:cohort;
rdf:predicate biolink:has_population_context;
rdf:subject sub:association;
nt:statementOrder "12"^^xsd:integer .
sub:st07b a rdf:Statement;
rdf:object sub:cohortAgeLabel;
rdf:predicate rdfs:label;
rdf:subject sub:cohort;
nt:statementOrder "13"^^xsd:integer .
sub:st07c a rdf:Statement;
rdf:object biolink:Cohort;
rdf:predicate biolink:category;
rdf:subject sub:cohort;
nt:statementOrder "14"^^xsd:integer .
sub:st08 a nt:OptionalStatement;
rdf:object sub:cohortAgeMin;
rdf:predicate schema:requiredMinAge;
rdf:subject sub:cohort;
nt:statementOrder "15"^^xsd:integer .
sub:st09 a nt:OptionalStatement;
rdf:object sub:cohortAgeMax;
rdf:predicate schema:requiredMaxAge;
rdf:subject sub:cohort;
nt:statementOrder "16"^^xsd:integer .
sub:st10 a nt:OptionalStatement, nt:RepeatableStatement;
rdf:object sub:hasPhenotype;
rdf:predicate biolink:has_phenotype;
rdf:subject sub:cohort;
nt:statementOrder "18"^^xsd:integer .
sub:st11 a rdf:Statement;
rdf:object rdf:Statement;
rdf:predicate rdf:type;
rdf:subject sub:association;
nt:statementOrder "20"^^xsd:integer .
sub:st12 a rdf:Statement;
rdf:object biolink:Drug;
rdf:predicate biolink:category;
rdf:subject sub:subject;
nt:statementOrder "23"^^xsd:integer .
sub:st13 a rdf:Statement;
rdf:object biolink:Disease;
rdf:predicate biolink:category;
rdf:subject sub:object;
nt:statementOrder "24"^^xsd:integer .
sub:st14 a rdf:Statement;
rdf:object biolink:treats;
rdf:predicate rdf:predicate;
rdf:subject sub:association;
nt:statementOrder "21"^^xsd:integer .
sub:subject a nt:GuidedChoicePlaceholder;
rdfs:label "search for the indicated drug";
nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .
rdf:Statement rdfs:label "association Statement" .
rdf:object rdfs:label "has disease" .
rdf:predicate rdfs:label "has predicate" .
rdf:subject rdfs:label "has drug" .
rdf:type rdfs:label "has type" .
rdfs:label rdfs:label "has label" .
schema:ApprovedIndication rdfs:label "An indication for a medical therapy that has been formally specified or approved by a regulatory body." .
schema:PreventionIndication rdfs:label "An indication for preventing an underlying condition, symptom, etc." .
schema:TreatmentIndication rdfs:label "An indication for treating an underlying condition." .
schema:requiredMaxAge rdfs:label "participant maximum age is" .
schema:requiredMinAge rdfs:label "participant minimum age is" .
biolink:EvidenceType rdfs:label "EvidenceType" .
biolink:association_type rdfs:label "has BioLink type" .
biolink:category rdfs:label "is a" .
biolink:description rdfs:label "is described by" .
biolink:has_drug rdfs:label "uses drug" .
biolink:has_phenotype rdfs:label "has phenotypes" .
biolink:has_population_context rdfs:label "has population context" .
biolink:id rdfs:label "has id" .
biolink:negated rdfs:label "is negated" .
biolink:provided_by rdfs:label "is provided by" .
biolink:publications rdfs:label "has publications" .
biolink:qualifiers rdfs:label "is qualified by" .
biolink:relation rdfs:label "has relation" .
nkg:OffLabelIndication rdfs:label "An indication found in off-label drug uses" .
nkg:SymptomaticReliefIndication rdfs:label "An indication for only managing the symptoms of the condition" .
}
sub:provenance {
sub:assertion prov:wasAttributedTo orcid:0000-0002-1501-1082 .
}
sub:pubinfo {
sub:sig npx:hasAlgorithm "RSA";
npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB";
npx:hasSignature "eKKcMOgi8sTLYjwEu6adzi76LP9NK1W4DLSu9CiJyt7+klEqyr8N+f+YV/2HipKPAW6Af0UtYI8E04ACowV69CMFhjujwj4HAdCDk3VROXM/D7qAP4gWKKiGca6hsBKh4C7mfZT2mTL6479wDY0DxXnzrxcbPIkbwu/A2hKREGQ=";
npx:hasSignatureTarget this: .
this: dcterms:created "2021-03-14T11:00:00+01:00"^^xsd:dateTime;
dcterms:creator orcid:0000-0002-1501-1082;
npx:supersedes <http://purl.org/np/RAZdZj78B6nKrP1Q00oFzsK07u7WdiY3sToz-H-H2nSgg> .
}